Levels of estrogen and progesterone in postmenopausal breast cancer patients

Abstract

This study was performed with an objective to compare the levels of estrogen and progesterone in postmenopausal breast cancer patient with age matched healthy controls. We performed a cross-sectional comparative study of two age matched groups of postmenopausal participants: 25 participants (cases) had carcinoma of breast and the other 25 participants (controls) were heathy females. The women with breast cancer had a mean age of 53.6 years and the heathy women had a mean age of 52.2 years. Blood samples were collected from all participants and assayed for serum estrogen and serum progesterone. The estrogen and progesterone levels in cases were significantly high as controls (p= <0.001 and p= <0.05 respectively). Estrogen levels were also significantly correlated with progesterone levels (r= 0.540, p< 0.05). In conclusion, study suggest that estrogen and progesterone should be routinely estimated in breast cancer patients for better treatment approaches as well as monitoring of disease progression.